Cas No. |
Product name |
1118807-13-8 |
KY02111 |
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KY02111 promotes differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, may act downstream of APC and GSK3β. |
1427782-89-5 |
IWP-L6 |
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IWP-L6 is a highly potent Porcn inhibitor with EC50 of 0.5 nM. |
1243243-89-1 |
Wnt-c59 |
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Wnt-C59 (C59) is a PORCN inhibitor for Wnt3A-mediated activation of a multimerized TCF-binding site driving luciferase with IC50 of 74 pM. |
1127442-82-3 |
IWR-1-endo |
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IWR-1-endo is a Wnt pathway inhibitor with IC50 of 180 nM, induces Axin2 protein levels and promotes β-catenin phosphorylation by stabilizing Axin-scaffolded destruction comp... |
108409-83-2 |
FH535 |
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FH535 is a Wnt/β-catenin signaling inhibitor and also a dual PPARγ and PPARδ antagonist. |
1123231-07-1 |
WAY-262611 |
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WAY-262611 is a wingless β-Catenin agonist that increases bone formation rate; with EC50 of 0.63 uM in TCF-Luciferase assay. |
950912-80-8 |
PF670462 |
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PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations. |
1638250-96-0 |
ETC-159 |
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ETC-159 is an effective and specific Wnt inhibitors and ETC-159 inhibit the activity of β--catenin gene IC50 for 2.9 nM, this effect is dose-dependent. |